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Objective:To analyze the status quo of occupational engagement of junior nurses and related influencing factors, and to provide reference for managers to develop a positive incentive mechanism.Methods:From November 2020 to December 2020, 255 junior nursing staff with less than or equal to 3 years seniority at 3 tertiary general hospitals in Tianjin were selected. Questionnaire surveys were made on their occupational engagement, occupational values, job satisfaction for nursing, and general self-efficacy. Descriptive analysis and t test were used to probe into their current occupational engagement, and build a relational model on the occupational satisfaction, and the relational model of between their occupational values and self-efficiency in general of these nursing staff. Results:The total scoring of the occupational engagement scale for 255 junior nursing staff was 78.47±19.93, which was higher than the domestic norm level, and the difference was statistically significant( t=11.48, P<0.001). The results of the structural equation model showed that the overall effect on the occupational engagement of junior nurses from high to low were as follows: self-efficacy( β=0.599), professional values( β=0.323)and job satisfaction( β=0.275). Conclusions:These nursing staff feature high occupational engagement. Hospital administrators are recommended to strength training, provide timely support and incentives for their sustained improvement of self-efficiency, meet their individual career development needs for higher job satisfaction, and focus on shaping their occupational values as well.
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Objective@#To translate the Pulmonary Embolism Quality of Life (PEmb-QoL) Scale into Chinese and evaluate its reliability and validity.@*Methods@#The Chinese version of PEmb-QoL was translated from the original, back-translated and adjusted for cultural adaptation.The reliability and validity were tested in 212 patients with PE.@*Results@#The content validity index (CVI) of the PEmb-QoL Scale was 0.910, which indicated a desirable content validity. Factor analysis ex-tracted six common factors, which explained 82.177% of variance of the total scale, and each item had high factor loading quantity (>0.4). The test-retest reliability was 0.810, and Cronbach α was 0.894.@*Conclusions@#Chinese version of PEmb-QoL has been proved to be valid and reliable. It is a valuable tool for evaluating the quality of life among patients with pulmonary embolism disease.
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Objective To translate the Pulmonary Embolism Quality of Life (PEmb-QoL) Scale into Chinese and evaluate its reliability and validity. Methods The Chinese version of PEmb-QoL was translated from the original,back-translated and adjusted for cultural adaptation.The reliability and validity were tested in 212 patients with PE. Results The content validity index (CVI) of the PEmb-QoL Scale was 0.910, which indicated a desirable content validity. Factor analysis ex-tracted six common factors, which explained 82.177% of variance of the total scale, and each item had high factor loading quantity (>0.4).The test-retest reliability was 0.810, and Cronbach α was 0.894. Conclusions Chinese version of PEmb-QoL has been proved to be valid and reliable.It is a valuable tool for evaluating the quality of life among patients with pulmonary embolism disease.
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Objective To quantify the workload rate of nurses at clinical departments and to clarify the current situation of clinical nursing work. Methods We randomly selected three departments respectively from the medical system and the surgery system as observation areas, and the nurses on the job as observation objects. Then we drew up the to-do-list of nursing work, and defined the concepts and activities of various items. The nurses of the department were observed and recorded every 5 minutes by uniformly-trained observers, and the data were collected and entered into the Excel software to set up the database by using the method of work sampling combined with the random starting point and other time intervals. Based on data collation and analysis of SPSS19. 0 statistical software, the improvement and control scheme was put forward. Results The average nursing workload rates of medicine and surgical systems were 93. 52％ and 92. 13％ respectively. Direct nursing in the surgical system accounted for 10. 59％, and indirect nursing accounted for 62. 89％; direct nursing for the medical system accounted for 16. 20％ and indirect nursing for 57. 32％. The proportions of nursing work belonged to operation increment were relatively large (77. 32％ and 81. 54％). Conclusions The work sampling method is more comprehensive and objective to reflect the intensity of nursing workload. To define the workload of clinical nurses and distinguish the increment and waste items of nursing process are helpful to improve the quality of nursing management and the efficiency of service.
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Objective To study the pharmacokinetics of aristolochic acid A in Radix Aristolochiae and the compound preparation of Guanxinsuhe Capsule in mice in vivo after single-dose oral administration and observe the difference of aristolochic acid A absorption and distribution. Methods Aristolochic acid A assay was performed by RP-HPLC on a Waters apparatus with a DiamonsilTM C18 column (250 mm × 4.6mm, 5 μm), a mobil phase: a mixture of methanol-water-acetic acid (72: 27 : 1), flow rate: 1.0 mL/min, detection wavelength: 315 nm, and column temperature: 20 ℃. Results Mice were given Radix Aristolochiae and Guanxinsuhe Capsule by ig at the same level of 2. 5 mg/kg of aristolochic acid A, respectively, which were suspended in 0. 3% CMC-Na solution. Plasma concentrations were determined by RPHPLC. After single-dose ig administration of Radix Aristolochiae or Guanxinsuhe Capsule to mice, the mean plasma concentration-time courses of aristolochic acid A obtained fitted the one-compartment model.The main pharmacokinetic parameters of aristolochic acid A in Radix Aristolochiae, t1/2ka, t1/2 ke, tmax,AUC, Cmax are 5. 103 min, 43. 63 min, 17.89 min, 80. 45 (μg · min)/mL, and 0. 916 8 μg/mL; the rela tive pharmacokinetic parameters in Guanxinsuhe Capsule are 5. 294 min, 43.50 min, 18. 32 min, 33.08(μg · min)/mL, and 0. 381 8 μg/mL. Conclusion The Cmax of aristolochic acid A in Guanxinsuhe Capsule is significantly less than that in Radix Aristolochiae, which indicates that the compound compability could decrease the absorption of aristolochiae acid A.
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AIM: To establish the quality standard for Guishao Soft Capsules(Radix Paeoniae Alba,Radix Angelicae Sinensis,Rhizoma Chuanxiong, etc.) METHODS: Radix Paeoniae Alba,Rhizoma Atractylodis,Rhizoma Chuanxiong,Rhizoma Alismatis and Radix Angelicae Sinensis were identified by TLC.The contents of albiflorin and paeoniflorin in Guishao Soft Capsules were determined by HPLC.HPLC analytical method was carried out(using) a C_(18) column and a mixture containing 17 volume of acetonitrile and 83 volume of 0.05% acetic acid as the mobile phase.The detection wavelength was set at 230 nm. RESULTS: Spots obtained from the test solutions had the same color in reference solution and medical material in the same location,and the blank solution had no interfernece.The linear range of albiflorin was from 0.53 ?g to 1.06 ?g(r=0.999 8),the average recovery was(100.3%.) The linear range of paeoniflorin was from 0.29 ?g to 2.00 ?g(r=0.999 9),the average recovery was(99.49%.) CONCLUSION: In TLC,the spots are very clear and specific to identify the herbal medicine in Guishao Soft Capsules.It is simple,quick,high precise and accurate for HPLC to control the quality of Guishao Soft Capsules.